Evidence-graded longevity guidance
Supplements, skincare actives and daily habits, each graded on the published research. What holds up goes into your plan. What doesn't goes on the Skip list.
Opening to a small first group. Free to apply.
Moderate activity, 15 min a day
Moderate evidence
Cohort of 416,175 adults in Taiwan: 15 min/day of moderate exercise was linked to 14% lower all-cause mortality. Observational.
Retinoid at night
LockedOne safety question first: are you pregnant, trying, or breastfeeding?
Oral collagen drinks
Early evidence · industry-funded
Private by design
Your plan is built in your browser. No answer is ever sent to us.
Rankings never for sale
Grades come from studies. No brand can pay its way up your plan.
Every claim, sourced
Each card links to the trials behind it, and is checked against them word for word.
01 — The method
An observational study is never allowed to say “reduces”. Mouse studies never rise above Weak. Two clinicians grade every card blind before it ships.
Strong
Large randomized trials, or a consistent meta-analysis of them, on real outcomes in people like you. No unresolved harm signal.
Moderate
Randomized trials on validated markers, or large consistent cohort studies on hard outcomes.
Early
Small, short or sponsor-dominated studies, or unvalidated markers only. Interesting, not settled.
Weak
Animal or lab evidence only, contradicted findings, or claims made only by the seller.
DoOn your own
Habits, over-the-counter products and devices with low risk.
DiscussWith your doctor
Prescriptions, procedures, or anything with a real harm signal. We never state a dose.
WatchNot yet
Active research with a named trial we're waiting on.
SkipSave your money
Weak evidence, harm outweighing benefit, or marketing that the trials don't back.
02 — How it works
01
Answer a few questions
Age band, sex, life stage and a handful of safety questions. “Prefer not to say” is always an option, and it never gets guessed for you.
02
Matched against the ledger
Your browser checks your answers against a signed, versioned ledger of graded cards. If the signature fails, nothing is shown.
03
Your plan, with receipts
Your top actions, what to discuss with a doctor, what to skip, and the studies behind each one.
03 — The Skip list
Free for everyone, always. Before you buy the next miracle product, check whether the trials agree with the label.
Oral collagen supplements
Benefits come mainly from industry-funded trials; independent trials contradict them.
Skip · EarlyCalcium + vitamin D for fracture prevention
Strong evidence of no benefit for fractures in adults living at home.
Skip · Strong, no benefitResearch peptides sold online
Animal and lab data only. Not tested in people for the uses they're sold for.
Skip · Weak04 — A living ledger
→New trials are searched for and triaged every day.
→A retracted study suspends its card automatically.
→Safety signals on supplements and cosmetics are tracked, not only benefits.
→Every change is published in a public changelog.